Neural Codes
Our lab investigates how the brain turns thought into action... (more)
We are also applying our knowledge of neural codes for movement to build prosthetic devices that provide an interface between the brain and the external world for individuals with paralysis... (more)
Truccolo, W., Friehs, G.M., Donoghue, J.P., Hochberg, L.R. (2008).
Primary Motor Cortex Tuning to Intended Movement Kinematics in Humans with Tetraplegia.
Journal of Neuroscience January 30, 2008, 28(5):1163-1178.
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supplemental text
Truccolo, W. & Donoghue, J.P., (2007)
Nonparametric Modeling of Neural Point Processes via Stochastic Gradient Boosting Regression.
Neural Computation, 19(3), 672-705.
PMID: 17298229 [PubMed - indexed for MEDLINE]
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Kim, S-P, Simeral JD, Hochberg LR, Donoghue JP, Friehs Gm, and Black MJ (2007)
Multi-state decoding of point-and-click control signals from motor cortical activity in a human with tetraplegia
Neural Engineering, 2007. CNE '07. 3rd International IEEE/EMBS Conference,
2-5 May 2007 Page(s):486 - 489
Digital Object Identifier 10.1109/CNE.2007.369715
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Vargas-Irwin C, Donoghue JP (2007) Automated spike sorting using density grid contour clustering and subtractive waveform decomposition. J Neurosci Methods. 2007 Aug 15;164(1):1-18. Epub 2007 Apr 12. PMID: 17512603 [PubMed - indexed for MEDLINE] doi:10.1016/j.jneumeth.2007.03.025
Donoghue JP, Hochberg LR, Nurmikko AV, Black MJ, Simeral JD, Friehs G (2007) Neuromotor prosthesis development. Med Health R I. 2007 Jan;90(1):12-5. No abstract available. PMID: 17487029 [PubMed - indexed for MEDLINE] http://www.health.ri.gov/publications/medhealthri/RIMed_Jan07CME.pdf
Aaron, R.K., Herr, H.M., Ciombor, D.McK., Hochberg, L.R., Donoghue, J.P., Briant, C.L., Morgan, J.R., and Ehrlich, M.G. (2006) Horizons in prosthesis development for restoration of limb function. J. Am. Accad. Ortho. Surg. 2006, 14(10), S198-204S
Abstract: http://www.jaaos.org/cgi/content/abstract/14/10/S198?ct=ct